Joinix TS Tablet

✔️ Uses of Joinix TS Tablet

• Osteoarthritis

✔️ How does Joinix TS Tablet work?

Joinix TS Tablet effectively reduces joint problems where chondroitin sulfate works by inhibiting certain cartilage-destroying substances and provides matrix components that maintain the structural strength of the bone, it also possesses anti-inflammatory properties which reduce joint inflammation. Glucosamine works by stimulating glycosaminoglycans which help in rebuilding the cartilage and reduce joint inflammation by inhibiting certain inflammatory substances.

✔️ Side Effects of Joinix TS Tablet

• Nausea
• Diarrhea
• Headache
• Tiredness
• Indigestion
• Constipation
• Abdominal pain
• Wind (flatulence)

✔️ Quick Suggestions:

• Glucosamine + Chondroitin helps in relieving symptoms of osteoarthritis.
• It may take several weeks to see treatment benefits. Keep taking the medicine as prescribed by your doctor.
• It may increase your blood sugar level. If you are diabetic, monitor your levels regularly.
• Side effects such as Nausea, Diarrhoea, abdominal pain, and indigestion may occur with Glucosamine + Chondroitin. These may not be with everyone. If any of the side effects other than those mentioned above occur, do consult the treating physician.
• Let your doctor know if your symptoms do not improve even after two to three months of taking the medication.

✔️ Indication of Joinix TS Tablet

While glucosamine and chondroitin sulfate supplements are commonly used for the management of osteoarthritis, their efficacy and safety in treating other conditions you mentioned, such as rheumatoid arthritis, migraines, psoriasis, vascular issues, kidney stones, and inflammatory bowel disease, have not been definitively established.

✔️ Pharmacology

Glucosamine, as a building block for glycosaminoglycans (GAGs), helps in the production of important substances like hyaluronic acid, keratan sulfate, and chondroitin sulfate. These substances contribute to the structure and function of articular cartilage, ligaments, tendons, and other connective tissues. By taking a supplement containing glucosamine sulfate, the body's glucosamine levels increase, supporting cartilage formation and repair. Glucosamine also stimulates the production of GAGs and proteoglycans by chondrocytes, the cells found in cartilage.

Chondroitin sulfate, another glycosaminoglycan found in connective tissue, acts as a proteoglycan substrate and helps protect healthy cartilage from premature deterioration. It accomplishes this by inhibiting the MMP enzyme, which breaks down proteoglycans.

When glucosamine and chondroitin sulfate are taken together, they exhibit a synergistic effect. This combination has shown particular success in treating the signs and symptoms of osteoarthritis, as well as slowing down its progression. Additionally, in healthy adults, it may help prevent the development of osteoarthritis. Compared to non-steroidal anti-inflammatory drugs (NSAIDs), glucosamine and chondroitin sulfate have demonstrated similar efficacy in treating osteoarthritis pain, but with better tolerability and clinical compliance. Furthermore, they can aid in the recovery of soft tissue injuries, such as strains in tendons or ligaments.

✔️ Dosage & Administration of Joinix TS Tablet

It's important to note that dosages can vary depending on factors such as body weight and individual response. The dosage recommendations you provided are as follows:

• Under 54 kg: 800 mg chondroitin sulfate & 1000 mg glucosamine sulfate per day
• 54 kg - 91 kg: 1200 mg chondroitin sulfate & 1500 mg glucosamine sulfate per day
• Over 91 kg: 1600 mg chondroitin sulfate & 2000 mg glucosamine sulfate per day

It is crucial to follow the instructions provided by your doctor or healthcare professional regarding the dosage and duration of the medication. It is generally recommended to swallow the tablets whole, without chewing, crushing, or breaking them. Joinix TS can be taken with or without food, but taking it at a fixed time can help with consistency.

✔️ Interaction

Drug-Drug Interactions: Glucosamine  + Chondroitin can interact with medicines used for blood thinning (Warfarin), medications for cancer (Paclitaxel), painkillers (Acetaminophen), and anti-diabetics (glimepiride, pioglitazone).

Drug-Food Interactions: Avoid intake of Vitamin E, St. John’s wort (antidepressant), and Ginkgo Biloba with Glucosamine  + Chondroitin. 

Drug-Disease Interactions: People dealing with impaired glucose tolerance, kidney or liver dysfunction risk factor for heart (cardiovascular) disease, and suffering from asthma should take Glucosamine  + Chondroitin with caution.

✔️ Contraindications

If you have any of these conditions

• Diabetes
• Heart disease
• Kidney disease
• Liver disease
• Stomach or intestinal problems
• An unusual or allergic reaction to chondroitin, glucosamine, sulfonamides, other supplements, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

✔️ Pregnancy & Lactation

the use of glucosamine sulfate or chondroitin sulfate supplements during pregnancy and breastfeeding is not recommended without proper medical advice. The effects of these supplements on a growing fetus have not been extensively studied, and their safety during pregnancy and nursing periods has not been established.

It is crucial for pregnant or breastfeeding women to consult with their healthcare providers before starting any new supplements, including glucosamine sulfate and chondroitin sulfate. Healthcare professionals can assess the potential risks and benefits and provide personalized recommendations based on individual circumstances.

During pregnancy and breastfeeding, it is important to prioritize the health and well-being of both the mother and the baby. Healthcare providers can guide women on alternative approaches or treatments that are safe and appropriate for their specific situation.

✔️ Precautions & Warnings

• Adopting a healthy lifestyle is essential for managing arthritic conditions. This includes maintaining healthy body weight, as obesity can contribute to joint pain.
• Engaging in physical activity, within the limits of your condition, can be beneficial. Low-impact aerobic activities such as treadmill walking, biking, swimming, and light weightlifting can help improve muscle strength and overall joint health. Avoid strenuous exercise that may worsen joint pain.
• Increasing your intake of glucosamine, chondroitin sulfate, vitamin D, and calcium-rich supplements can support joint health. Turmeric and fish oil supplements, which have anti-inflammatory properties, may also be beneficial.
• Including fish rich in omega-3 fatty acids, such as salmon, trout, tuna, and sardines, in your diet can help reduce inflammation and protect the heart.
• Maintaining a good sitting posture, using supports like a rolled-up towel for the back curve, and using a footrest if necessary can alleviate pain and discomfort.
• Applying a cold or hot compress to the joints on a regular basis for 15-20 minutes can provide relief. Heat therapy can help relax muscles and improve circulation, while cold therapy can help reduce inflammation and numb pain.
• Practicing relaxation techniques like meditation, reading, taking baths, or listening to calming music can help manage stress, which can contribute to pain perception.
• Avoiding alcohol consumption and quitting smoking are recommended. Alcohol can increase the risk of liver damage, and smoking can have negative effects on overall health, including joint health.

✔️ Storage Conditions

Keep out of the reach of children and pets. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) or as directed on the package label. Protect from moisture. Throw away any unused supplement after the expiration date.